Transcriptional control and hormonal response of thermogenic fat
نویسندگان
چکیده
منابع مشابه
Transcriptional control and hormonal response of thermogenic fat.
Obesity and its associated metabolic diseases present a major public health problem around the world. The discovery that thermogenic fat is active in adult humans has sparked a renewal of interest in the study of its development and function and in the feasibility of using modulators of thermogenesis to work against obesity. In recent years, it has been shown that there are at least two distinc...
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Hormones exert powerful influences on body fat distribution in humans. Studies under fully controlled conditions in vitro have indicated that cortisol and insulin facilitate lipid accumulation by expressing lipoprotein lipase (LPL). Growth hormone (GH) abolishes this and turns metabolism towards lipid mobilization. Testosterone and GH inhibit LPL and stimulate lipolysis markedly. Cortisol effec...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2015
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-15-0026